DMEK is an advanced, minimally invasive corneal transplant technique that selectively replaces the damaged inner endothelial layer, restoring vision in conditions like Fuch’s Dystrophy.
The surgeon carefully removes the patient’s diseased endothelial layer and inserts a paper-thin donor graft consisting of healthy Descemet’s membrane and endothelium. This ultra-thin graft is floated into place using fluid and an air bubble, which holds it against the back of the cornea until it attaches naturally.
Excellent visual outcomes with potential for 20/20 vision
Minimally invasive – only a thin inner layer is replaced
Low risk of rejection (less than 1%)
Quick visual recovery (often within weeks)
Minimal change to the corneal curvature (less induced astigmatism)
Day-case procedure with local anaesthetic
DMEK is ideal for patients with:
Fuch’s Endothelial Dystrophy
Pseudophakic bullous keratopathy
Failed previous endothelial grafts
It requires a clear corneal stroma and good surgical access. Not suitable for patients with severe ocular surface disease or anatomical abnormalities (e.g. shallow anterior chambers).
Lie flat (face-up) for 24–48 hours as advised
Avoid strenuous activity or eye rubbing
Use prescribed steroid and antibiotic eye drops
Expect vision to improve within 1–4 weeks
Attend follow-up visits to monitor graft adhesion and pressure
Occasionally, a top-up air injection (“rebubbling”) may be needed if graft detaches partially
DMEK should be considered:
When Fuch’s Dystrophy affects quality of life (persistent blur, glare, visual loss)
If medical therapy no longer controls corneal swelling
Before corneal decompensation leads to permanent scarring
Lie flat (face-up) for 24–48 hours as advised
Avoid strenuous activity or eye rubbing
Use prescribed steroid and antibiotic eye drops
Expect vision to improve within 1–4 weeks
Attend follow-up visits to monitor graft adhesion and pressure
Occasionally, a top-up air injection (“rebubbling”) may be needed if graft detaches partially
